Relationship of HbA1c with Fasting Blood Glucose on Diagnostic Values and Lifestyle in Type II Diabetes Mellitus Patients
Hubungan HbA1c dengan Glukosa Darah Puasa terhadap Nilai Diagnostik dan Pola Hidup pada Penderita Diabetes Mellitus Tipe II
Early diagnosis of DM (Diabetes Mellitus) is very important in reducing complications. HbA1c has been recommended as a diagnosis of diabetes in the guidelines for clinical practice as a determination of type 2 diabetes in 2011 by WHO, but is there a significant relationship between HBA1c and fasting blood glucose levels (GDP) in a person after being diagnosed with Diabetes Mellitus. In this study, the relationship between HbA1c and GDP levels was assessed through observational cross-sectional analytic based studies. The research method uses a large sample selected through the GDP test (> 125 mg / dl) of 17 people (5 men and 12 women). Statistical analysis of the test of the relationship between the HbA1c results and GDP with the Pearson Correlation, Crosstabs, and independent T test to determine the relationship of sex with GDP and HBA1c. The results of the study, there was a significant relationship between levels of GDP with HBA1c with p = 0.002, where the incidence of GDP (> 125 mg / dl) in men was 17.7% and women were 52.9%, while the results of HBA1c (> 6.5 %) in men 23.5% and women 52.9%. In conclusion, the results of HBA1c (> 6.5%) can be used for diagnosis of DM, whereas the level of GDP is only to know that people with diabetes have changed their lifestyle or not, and it is found that women are more easily change lifestyles than men, due to GDP results (<125 mg / dl) of 11.8% higher than the HBA1c yield (<6.5%) of 5.9%.
American Diabetes Association (ADA). (2010). Diagnosis and Classification of Diabetes Mellitus. Diabetes Care, 33(Suppl 1), S62–S69. doi: 10.2337/dc10-S062
Davis, N. J., Tomuta, N., Schechter, C., Isasi, C. R, Segal-Isaacson, C. J., Stein, D., Zonszein, J., & Wylie-Rosett J., (2009). Comparative study of the effects of a 1-year dietary intervention of a low-carbohydrate diet versus a low-fat diet on weight and glycemic control in type 2 diabetes. Diabetes Care, 32(7), 1147-52. doi: doi.org/10.2337/dc08-2108
Diabetes.co.uk. (2019). Blood Sugar Level Ranges. Retrieved from https://www.diabetes.co.uk/diabetes_care/blood-sugar-level-ranges.html
Ghazanfari, Z., Haghdoost, A. S., Alizadeh, S. M., Atapour, J., & Zolala, F. (2010). A Comparison of HbA1c and Fasting Blood Sugar Tests in General Population. Int J Prev Med, 1(3), 187-94. Retrieved from https://pubmed.ncbi.nlm.nih.gov/21566790/
IDF Diabetes Atlas 7th Edition. (2015). Retrieved from https://www.oedg.at/pdf/1606_IDF_Atlas_2015_UK.pdf
Jumaah, I. A. M. (2016). Comparison between Fasting Plasma Glucose and HbA1c in Glycemic Control of Type-2 Diabetic Patients. Journal of Babylon University/Pure and Applied Sciences, 24(9), 1-12. Retrieved from https://www.iasj.net/iasj?func=fulltext&aId=119670
Kilpatrick, E. S., Rigby, A. S., & Atkin, S. L. (2006). The effect of glucose variability on the risk of microvascular complications in type 1 diabetes. Diabetes Care, 29(7), 1486-90. doi: 10.2337/dc06-0293.
Reinauer, H., Home, P. D., Kanagasabapathy, A. S., & Heuck, C. C. (2002). Laboratory Diagnosis and Monitoring of Diabetes Melitus. Geneva, Switzerland: WHO Press. Retrieved from https://www.paho.org/hq/dmdocuments/2012/WHO-Laboratory-Diagnosis-Diabetes-2002.pdf
Ripsin, C. M., Kang, H., & Urban, R.J. (2009). Management of blood glucose in type 2 diabetes mellitus. Am Fam Physician, 79(1), 29-36. Retrieved from https://pubmed.ncbi.nlm.nih.gov/19145963/
World Health Organization (WHO). (2011). Use of Glycated Haemoglobin (HbA1c) in the Diagnosis of Diabetes Mellitus. WHO/NMH/CHP/CPM/11.1, 1-25. Retrieved from https://www.who.int/diabetes/publications/report-hba1c_2011.pdf
World Health Organization (WHO). (2016). Global Report On Diabetes. Geneva, Switzerland: WHO Press. Retrieved from https://apps.who.int/iris/bitstream/handle/10665/204871/9789241565257_eng.pdf;jsessionid=8BD2AC212A2A26533DA8E0621D2BF1D3?sequence=1